Swiss-Model

An Automated Knowledge-based Protein Modelling Server

Introduction:

Swiss-Model is an Automated Protein Modelling Server running at the GLAXO Institute for Molecular Biology in Geneva, Switzerland (GIMB).

The purpose of this server is to make Protein Modelling accessible to all biochemists and molecular biologists World Wide.

The present version of the server is 2.1 and is under constant improvement and debugging. In order to help us refine the sequence analysis and modelling algorithms, please submit requests to the server and report of possible bugs and problems with the modelling procedure.

New: The G-protein coupled Receptor modelling tool is now available.

Please look at the Swiss-PdbViewer, our new Macintosh tool for structure display and analysis, which is under development in Geneva.

Please have a look at Frequently Asked Questions and Swiss-Model Help.

The result of any modelling procedure is NON-EXPERIMENTAL and MUST be considered with care. This is especially true since there is no human intervention during model building.

How to Access Swiss-Model:

You may access Swiss-Model from here and submit your requests through these forms:

First Approach mode Allows you to determine if a particular sequence can be modelled. If this is possible, you will get a first model for it, as well as the files needed for the Optimise mode.
Optimise mode Allows fine tuning of the modelling performed in the First Approach mode.
GPCR/7TM mode Interface to the G-protein coupled receptor modelling mode of the server.

A few links related to Protein Structure:

The links marked by local

are local to the ExPASy server. The remaining ones are pointers to other servers:

The Swiss-3DImage Collection.
The Swiss-3DBrowser.
The Brookhaven Data Base Browser and their Home Page.
Structural Classification of Proteins.
The Protein Science Server.
Molecular Modeling at the NIH.
Molecules R US at the NIH.
An Internet Course on The Principles of Protein Structure.
The group of Chris Sander at the EMBL and the DALI Server.
The BioTech Protein Verification Server.
The Structural Biology Group at BNL.
The Protein Structure group at the University of York.
Employment available in crystallography

If you have problems or comments...

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